Contract Research

Charles River Laboratories International, Inc. provides essential products and services to help pharmaceutical and biotechnology companies, government agencies and leading academic institutions around the globe accelerate their research and drug development efforts. Dedicated employees are focused on providing clients with exactly what they need to improve and expedite the discovery, early-stage development and safe manufacture of new therapies for the patients who need them.

The Charles River location in Skokie specializes in genetic and in vitrotoxicology assessments and immunoassay services, including quantitative PK/TK assays, immunogenicity testing such as neutralizing antibody assays (cell based, binding or enzymatic), and biomarkers. To learn more about the Charles River unique portfolio and breadth of services, click here.

 

Exicure, formerly AuraSense Therapeutics, is developing a new class of immunomodulatory and gene silencing drugs against validated targets. Our 3-dimensional, spherical nucleic acid (SNA™) architecture unlocks the potential of nucleic acid therapeutics in multiple organs. Our lead programs address diseases from inflammatory disorders to oncology.

SNA constructs overcome one of the most difficult obstacles to nucleic acid therapeutics: safe and effective delivery into cells and tissues. SNA constructs exhibit unparalleled transfection efficiency into numerous cell and tissue types including the skin without carriers or transfection agents. Moreover, SNAs can be used as potent immunotherapeutic agents for the treatment of cancer or infectious disease.

Midwest NeuroResearch Institute (MNRI) is a provider of preclinical and clinical research services.  Our research extends to behavioral, cognitive, sentient, and motor-related effects of drugs of abuse - especially the opioids, GHB, cannabinoids and barbiturates, relative to their impact on specific brain sites and receptors.  Of special interest are sites and mechanisms of the ascending DA pathways impacted by these drugs.  MNRI research also extends to clinical cases involving neuro-trauma; especially brain injuries that involve these and other neurotoxic agents, including their cause and full extent.  As a research provider exclusively, MNRI does not offer medical advice or treatment of any kind to patients.